Pub. Date : 2004 Mar 16
PMID : 14694147
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | XOR is a member of the molybdoenzyme family and is best known for its catalytic role in purine degradation, metabolizing hypoxanthine and xanthine to uric acid with concomitant generation of superoxide. | Superoxides | xanthine dehydrogenase | Homo sapiens |
| 2 | XOR requires molybdopterin, iron-sulphur centres, and FAD as cofactors and has two interconvertible forms, xanthine oxidase and xanthine dehydrogenase, which transfer electrons from xanthine to oxygen and NAD(+), respectively, yielding superoxide, hydrogen peroxide and NADH. | Superoxides | xanthine dehydrogenase | Homo sapiens |
| 3 | XOR requires molybdopterin, iron-sulphur centres, and FAD as cofactors and has two interconvertible forms, xanthine oxidase and xanthine dehydrogenase, which transfer electrons from xanthine to oxygen and NAD(+), respectively, yielding superoxide, hydrogen peroxide and NADH. | Superoxides | xanthine dehydrogenase | Homo sapiens |
| 4 | Additionally, XOR can generate superoxide via NADH oxidase activity and can produce nitric oxide via nitrate and nitrite reductase activities. | Superoxides | xanthine dehydrogenase | Homo sapiens |