Pub. Date : 2003 Dec
PMID : 14679178
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Uncoupling protein 2 (UCP2), by virtue of its mitochondrial proton leak activity and consequent negative effect on ATP production, impairs glucose-stimulated insulin secretion. | Adenosine Triphosphate | uncoupling protein 2 | Homo sapiens |
| 2 | Uncoupling protein 2 (UCP2), by virtue of its mitochondrial proton leak activity and consequent negative effect on ATP production, impairs glucose-stimulated insulin secretion. | Adenosine Triphosphate | uncoupling protein 2 | Homo sapiens |
| 3 | This study demonstrates that endogenously produced mitochondrial superoxide activates UCP2-mediated proton leak, thus lowering ATP levels and impairing glucose-stimulated insulin secretion. | Adenosine Triphosphate | uncoupling protein 2 | Homo sapiens |