Title : The 2.0 A resolution crystal structure of prostaglandin H2 synthase-1: structural insights into an unusual peroxidase.

Pub. Date : 2004 Jan 9

PMID : 14672659






1 Functional Relationships(s)
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1 We present here the 2.0 A resolution X-ray crystal structure of ovine prostaglandin H2 synthase-1 in complex with alpha-methyl-4-biphenylacetic acid, a defluorinated analog of the non-steroidal anti-inflammatory drug flurbiprofen. Flurbiprofen prostaglandin-endoperoxide synthase 1 Homo sapiens