Pub. Date : 2004
PMID : 14667437
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Knockdown of spinal cord postsynaptic density protein-95 prevents the development of morphine tolerance in rats. | Morphine | discs large MAGUK scaffold protein 4 | Rattus norvegicus |
| 2 | Co-administration of morphine twice daily and PSD-95 antisense oligodeoxynucleotide (50 microg/10 microl) once daily for 4 days not only markedly reduced the PSD-95 expression and its binding to NMDA receptors in spinal cord but also significantly prevented the development of morphine tolerance. | Morphine | discs large MAGUK scaffold protein 4 | Rattus norvegicus |
| 3 | Co-administration of morphine twice daily and PSD-95 antisense oligodeoxynucleotide (50 microg/10 microl) once daily for 4 days not only markedly reduced the PSD-95 expression and its binding to NMDA receptors in spinal cord but also significantly prevented the development of morphine tolerance. | Morphine | discs large MAGUK scaffold protein 4 | Rattus norvegicus |