Title : Role of multiple drug resistance protein 1 in neutral but not acidic glycosphingolipid biosynthesis.

Pub. Date : 2004 Feb 27

PMID : 14662772






1 Functional Relationships(s)
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1 Metabolic labeling in wild type and knock-out (MDR1a, 1b, MRP1) mouse fibroblasts showed the same loss of neutral glycosphingolipid (glucosyl ceramide, lactosyl ceramide) but not ganglioside (GM3) synthesis, confirming the proposed role for MDR1 translocase activity. Glucosylceramides ATP-binding cassette, sub-family B (MDR/TAP), member 1A Mus musculus