Title : Desensitisation of mast cell beta2-adrenoceptor-mediated responses by salmeterol and formoterol.

Pub. Date : 2004 Jan

PMID : 14662724






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The desensitisation induced by long-term treatments with salmeterol and formoterol was specific for beta(2)-adrenoceptor-mediated inhibition of histamine release as the inhibitory effects of alternative cAMP-elevating compounds, prostaglandin E(2), a receptor-mediated activator of adenylate cyclase, and forskolin, a direct activator of adenylate cyclase, were unaffected by desensitising treatments. Colforsin adrenoceptor beta 2 Homo sapiens