Pub. Date : 2003 Dec
PMID : 14645667
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The stress-inducible transcription factor known as growth and DNA damage (GADD)-inducible transcription factor 153 is induced in response to fenretinide and in other cell types modulates apoptosis via pro- and antiapoptotic members of the BCL2 family. | Fenretinide | BCL2 apoptosis regulator | Homo sapiens |
2 | Because BCL2-family proteins are important in apoptosis induced by chemotherapeutic drugs, GADD153 may be a key mediator of synergy between fenretinide and chemotherapeutic drugs. | Fenretinide | BCL2 apoptosis regulator | Homo sapiens |