Title : Transient induction of cytochromes P450 1A1 and 1B1 in MCF-7 human breast cancer cells by indirubin.

Pub. Date : 2003 Dec 15

PMID : 14637189






2 Functional Relationships(s)
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1 Thus, if indirubin is an endogenous AhR ligand, then AhR-mediated signaling by indirubin is likely to be transient and tightly controlled by the ability of indirubin to induce CYP1A1 and CYP1B1, and hence its own metabolism. indirubin aryl hydrocarbon receptor Homo sapiens
2 Thus, if indirubin is an endogenous AhR ligand, then AhR-mediated signaling by indirubin is likely to be transient and tightly controlled by the ability of indirubin to induce CYP1A1 and CYP1B1, and hence its own metabolism. indirubin aryl hydrocarbon receptor Homo sapiens