Title : Benzo(a)pyrene quinones increase cell proliferation, generate reactive oxygen species, and transactivate the epidermal growth factor receptor in breast epithelial cells.

Pub. Date : 2003 Nov 15

PMID : 14633709






2 Functional Relationships(s)
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Protein Name
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1 Using a model of epidermal growth factor (EGF) withdrawal in MCF-10A, we hypothesized that production of reactive oxygen species by BPQs could lead to the activation of the EGF receptor (EGFR). Reactive Oxygen Species epidermal growth factor receptor Homo sapiens
2 Using a model of epidermal growth factor (EGF) withdrawal in MCF-10A, we hypothesized that production of reactive oxygen species by BPQs could lead to the activation of the EGF receptor (EGFR). Reactive Oxygen Species epidermal growth factor receptor Homo sapiens