Title : Arsenic trioxide induces apoptosis of cutaneous T cell lymphoma cells: evidence for a partially caspase-independent pathway and potentiation by ascorbic acid (vitamin C).

Pub. Date : 2003 Oct

PMID : 14632209






1 Functional Relationships(s)
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1 As2O3-induced Sezary cell death involves activation of caspase-3, cleavage of poly(ADP-ribose)polymerase, and cytochrome c release, but was only partially inhibited by the pancaspase inhibitor Z-VAD.fluoromethylketone. fluoromethylketone poly(ADP-ribose) polymerase 1 Homo sapiens