Pub. Date : 2003 Nov 25
PMID : 14621991
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Identification of nicotinic acetylcholine receptor amino acids photolabeled by the volatile anesthetic halothane. | Halothane | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 2 | To identify inhalational anesthetic binding domains in a ligand-gated ion channel, we photolabeled nicotinic acetylcholine receptor (nAChR)-rich membranes from Torpedo electric organ with [(14)C]halothane and determined by Edman degradation some of the photolabeled amino acids in nAChR subunit fragments isolated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and high-performance liquid chromatography. | Halothane | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 3 | Halothane photolabeling of deltaTyr-228 provides initial evidence that halothane and isoflurane bind within this pocket with occupancy or access increased in the nAChR desensitized state compared to the closed channel state. | Halothane | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 4 | Halothane photolabeling of deltaTyr-228 provides initial evidence that halothane and isoflurane bind within this pocket with occupancy or access increased in the nAChR desensitized state compared to the closed channel state. | Halothane | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |