Pub. Date : 2003 Nov
PMID : 14617794
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cell adhesion to fibronectin and phosphorylation of focal adhesion kinase (FAK), which are associated with alpha5beta1 integrin and involved in a cell survival signaling, were found to be increased in the cisplatin-resistant cells. | Cisplatin | protein tyrosine kinase 2 | Homo sapiens |
| 2 | Cell adhesion to fibronectin and phosphorylation of focal adhesion kinase (FAK), which are associated with alpha5beta1 integrin and involved in a cell survival signaling, were found to be increased in the cisplatin-resistant cells. | Cisplatin | protein tyrosine kinase 2 | Homo sapiens |
| 3 | Interestingly, the differences in sensitivity to cisplatin and FAK phosphorylation between cisplatin-sensitive and -resistant cells were completely abolished by treatment with a neutral antibody of alpha5beta1 integrin. | Cisplatin | protein tyrosine kinase 2 | Homo sapiens |