Title : Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells.

Pub. Date : 2003 Nov 13

PMID : 14614451






2 Functional Relationships(s)
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1 In other studies, we observed that G2/M arrest by silibinin was associated with a decrease in cdc25C, cdc2/p34 and cyclin B1 protein levels, as well as cdc2/p34 kinase activity. Silybin cyclin dependent kinase 1 Homo sapiens
2 In other studies, we observed that G2/M arrest by silibinin was associated with a decrease in cdc25C, cdc2/p34 and cyclin B1 protein levels, as well as cdc2/p34 kinase activity. Silybin cyclin dependent kinase 1 Homo sapiens