Title : Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin.

Pub. Date : 2003 Sep

PMID : 14604466






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Rifampicin (20 microM) increased CYP2E1 protein by 2.1 fold, while 10 microM bupropion minimally altered CYP2E1 protein (1.2 fold). Bupropion cytochrome P450 family 2 subfamily E member 1 Homo sapiens