Title : Loss of p53 has site-specific effects on histone H3 modification, including serine 10 phosphorylation important for maintenance of ploidy.

Pub. Date : 2003 Oct 15

PMID : 14583461






2 Functional Relationships(s)
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1 Abnormal S10P in p53-/- cells was also observed under completely different experimental conditions where cells were treated with nocodazole to induce G(2)-M arrest and elevation of S10P (which is linked with G(2)-M of the cell cycle). Nocodazole tumor protein p53 Homo sapiens
2 On removal of nocodazole, the p53+/+ cells exhibited rapid reduction in S10P levels and cell cycle recovery. Nocodazole tumor protein p53 Homo sapiens