Title : Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity.

Pub. Date : 2004 Jan 9

PMID : 14573608






2 Functional Relationships(s)
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1 Under conditions where rapamycin inhibited proliferation, p27kip1 down-regulation was prevented, whereas under conditions resulting in rapamycin-resistant proliferation, p27kip1 was down-regulated. Sirolimus cyclin dependent kinase inhibitor 1B Homo sapiens
2 Under conditions where rapamycin inhibited proliferation, p27kip1 down-regulation was prevented, whereas under conditions resulting in rapamycin-resistant proliferation, p27kip1 was down-regulated. Sirolimus cyclin dependent kinase inhibitor 1B Homo sapiens