Title : Epigallocatechin gallate protects nerve growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase kinase-3.

Pub. Date : 2003 Oct 21

PMID : 14559356






1 Functional Relationships(s)
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1 EGCG or z-VAD-fmk-pretreated PC12 cells showed an increase of viability compared to untreated PC12 cells, and pretreatment of PC12 cells with either agent induced a dose-dependent inhibition of caspase-3 activation and PARP cleavage. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone caspase 3 Rattus norvegicus