Title : Modulation of angiotensin II-mediated signalling by heparan sulphate glycosaminoglycans.

Pub. Date : 2003 Nov

PMID : 14551349






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Heparin inhibited NF-kappaB activation in Ang II-stimulated MCs that expressed either normal or chemically altered GAG. Glycosaminoglycans angiotensinogen Homo sapiens
2 CONCLUSIONS: These findings suggest that alterations in HS-GAG chemistry or metabolism under pathological conditions, such as DN, may have direct functional consequences for the local effect of Ang II. Glycosaminoglycans angiotensinogen Homo sapiens