Pub. Date : 2003 Nov
PMID : 14532843
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Subsequently the dose dependent effect of dihydrotestosterone (DHT) on BCG induced IL-6 expression and NF-kappaB signaling was evaluated. | Dihydrotestosterone | interleukin 6 | Homo sapiens |
| 2 | Subsequently the dose dependent effect of dihydrotestosterone (DHT) on BCG induced IL-6 expression and NF-kappaB signaling was evaluated. | Dihydrotestosterone | interleukin 6 | Homo sapiens |
| 3 | DHT suppressed BCG induced, NF-kappaB mediated signaling and IL-6 expression in a dose dependent manner. | Dihydrotestosterone | interleukin 6 | Homo sapiens |
| 4 | DHT decreased mRNA levels of IL-6, expression of the full-length IL-6 promoter construct and expression of an NF-kappaB specific reporter construct in response to BCG relative to controls. | Dihydrotestosterone | interleukin 6 | Homo sapiens |
| 5 | DHT decreased mRNA levels of IL-6, expression of the full-length IL-6 promoter construct and expression of an NF-kappaB specific reporter construct in response to BCG relative to controls. | Dihydrotestosterone | interleukin 6 | Homo sapiens |
| 6 | CONCLUSIONS: DHT down-regulates NF-kappaB mediated IL-6 expression by human TCC lines in response to BCG. | Dihydrotestosterone | interleukin 6 | Homo sapiens |