Title : Acute and chronic effects of nicotine on serotonin uptake in prefrontal cortex and hippocampus of rats.

Pub. Date : 2003 Dec 1

PMID : 14515338






6 Functional Relationships(s)
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1 We sought to investigate the effect of nicotine exposure (chronic and acute) on serotonin transporter (SERT) activity in two regions of the brain important for behavioral effects of nicotine. Nicotine solute carrier family 6 member 4 Rattus norvegicus
2 We sought to investigate the effect of nicotine exposure (chronic and acute) on serotonin transporter (SERT) activity in two regions of the brain important for behavioral effects of nicotine. Nicotine solute carrier family 6 member 4 Rattus norvegicus
3 We sought to investigate the effect of nicotine exposure (chronic and acute) on serotonin transporter (SERT) activity in two regions of the brain important for behavioral effects of nicotine. Nicotine solute carrier family 6 member 4 Rattus norvegicus
4 We sought to investigate the effect of nicotine exposure (chronic and acute) on serotonin transporter (SERT) activity in two regions of the brain important for behavioral effects of nicotine. Nicotine solute carrier family 6 member 4 Rattus norvegicus
5 SERT binding studies, using prefrontocortical or hippocampal membrane preparations, revealed that chronic nicotine exposure significantly increased B(max) which correlated to an increase in SERT density. Nicotine solute carrier family 6 member 4 Rattus norvegicus
6 SERT binding studies, using prefrontocortical or hippocampal membrane preparations, revealed that chronic nicotine exposure significantly increased B(max) which correlated to an increase in SERT density. Nicotine solute carrier family 6 member 4 Rattus norvegicus