Title : Relationship of trichothecene structure to COX-2 induction in the macrophage: selective action of type B (8-keto) trichothecenes.

Pub. Date : 2003 Oct 24

PMID : 14514436






1 Functional Relationships(s)
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1 Taken together, Type B trichothecenes selectively enhanced transcription and stabilization of the COX-2 gene, and this was mediated by the ERK 1/2 and p38 signaling pathways. Trichothecenes mitogen-activated protein kinase 3 Mus musculus