Title : Increased dopamine and its metabolites in SH-SY5Y neuroblastoma cells that express tyrosinase.

Pub. Date : 2003 Oct

PMID : 14511124






3 Functional Relationships(s)
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1 Increased dopamine and its metabolites in SH-SY5Y neuroblastoma cells that express tyrosinase. Dopamine tyrosinase Homo sapiens
2 Overexpression of tyrosinase in cultured cell lines resulted in (i) increased intracellular dopamine content; (ii) induction of oxidase activity not only for DOPA but also for dopamine; (iii) formation of melanin pigments in cell soma; and (iv) increased intracellular reactive oxygen species. Dopamine tyrosinase Homo sapiens
3 Overexpression of tyrosinase in cultured cell lines resulted in (i) increased intracellular dopamine content; (ii) induction of oxidase activity not only for DOPA but also for dopamine; (iii) formation of melanin pigments in cell soma; and (iv) increased intracellular reactive oxygen species. Dopamine tyrosinase Homo sapiens