Title : Cyclosporin A protects hepatocytes against prooxidant-induced cell killing. A study on the role of mitochondrial Ca2+ cycling in cytotoxicity.

Pub. Date : 1992 Nov 17

PMID : 1449518






2 Functional Relationships(s)
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1 Measurement of the intracellular Ca2+ pools showed an early depletion of the mitochondrial Ca2+ pool in hepatocytes exposed to 3,5-Me2-NAPQI, tBH or cumene hydroperoxide; this loss was prevented by CsA. tert-Butylhydroperoxide carbonic anhydrase 2 Homo sapiens
2 Measurement of the intracellular Ca2+ pools showed an early depletion of the mitochondrial Ca2+ pool in hepatocytes exposed to 3,5-Me2-NAPQI, tBH or cumene hydroperoxide; this loss was prevented by CsA. tert-Butylhydroperoxide carbonic anhydrase 2 Homo sapiens