Title : High- and low-affinity binding of GRO alpha and neutrophil-activating peptide 2 to interleukin 8 receptors on human neutrophils.

Pub. Date : 1992 Nov 1

PMID : 1438244






1 Functional Relationships(s)
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1 Treatment of membranes with digitonin resulted in the preferential solubilization of a single receptor species, corresponding to p44, that bound GRO alpha and NAP-2 with low affinity (Kd = 30 nM) and IL-8 with high affinity (Kd = 0.4 nM). Digitonin pro-platelet basic protein Homo sapiens