Title : Alterations in renal endothelin-1 production in the spontaneously hypertensive rat.

Pub. Date : 1992 Nov

PMID : 1428117






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Endothelin-1 inhibits sodium and water transport systems in the inner medullary collecting duct. Sodium endothelin 1 Rattus norvegicus
2 Endothelin-1 levels are reduced in the medulla of spontaneously hypertensive rats (SHR), raising the possibility that decreased inner medullary collecting duct production of endothelin-1 could contribute to inappropriate sodium and water retention. Sodium endothelin 1 Rattus norvegicus