Title : Effect of nonpeptide angiotensin receptor antagonists on water intake and salt appetite in rats.

Pub. Date : 1992 Sep-Oct

PMID : 1393612






2 Functional Relationships(s)
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1 The AT-1 receptor blocker, losartan potassium (DUP 753), inhibited water intake evoked by central administration of AII, with the 50% inhibitory dose being less than 0.1 microgram. Water angiotensin II receptor, type 1a Rattus norvegicus
2 These data suggest that both AT-1 and AT-2 receptor subtypes in the brain are involved in angiotensin-related water and NaCl intakes. Water angiotensin II receptor, type 1a Rattus norvegicus