Pub. Date : 1992 Oct
PMID : 1383494
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In the presence of 5 U/ml of heparin to block [125I]aFGF binding to membrane bound heparan sulfate proteoglycans, specific [125I]aFGF binding was optimal in the presence of 0.2 M NaCl and in a pH range of 7 to 9. | Heparitin Sulfate | fibroblast growth factor 1 | Homo sapiens |
2 | However, at a low heparin concentration (0.1 U/ml), [125I]aFGF binds to the FGF-flg receptor with higher affinity than was observed in the presence of 5 U/ml of heparin, and also binds a class of lower affinity recognition sites which are consistent with the labeling of cell surface heparan sulfate proteoglycans. | Heparitin Sulfate | fibroblast growth factor 1 | Homo sapiens |