| Protein Name | fibroblast growth factor 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 2246 |
| Gene Symbol | FGF1 |
| UniProt | P05230 (FGF1_HUMAN), A8K147 (A8K147_HUMAN), Q16089 (Q16089_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
365
Total Number of Articles : 473 |
Description |
fibroblast growth factor 1 |
| Gene Summary |
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009] |
| synonyms |
|
| Properties | |