Title : Sulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase C gamma 1.

Pub. Date : 1992 Jan 1

PMID : 1370350






1 Functional Relationships(s)
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1 However, CD3-induced signaling was inhibited at N-ethylmaleimide concentrations lower than that required for CD4/pp56lck dissociation, suggesting that CD3-associated tyrosine kinase activity involves acutely sensitive regulatory thiols. Sulfhydryl Compounds CD4 molecule Homo sapiens