Pub. Date : 2004 Jan
PMID : 13679307
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Isoform activity was demonstrated by cytosol-to-membrane translocation after PMA treatment and phosphorylation of the myristoylated alanine-rich C kinase substrate (MARCKS) protein after PMA and DAG treatment. | Diglycerides | myristoylated alanine rich protein kinase C substrate | Homo sapiens |
2 | Isoform activity was demonstrated by cytosol-to-membrane translocation after PMA treatment and phosphorylation of the myristoylated alanine-rich C kinase substrate (MARCKS) protein after PMA and DAG treatment. | Diglycerides | myristoylated alanine rich protein kinase C substrate | Homo sapiens |
3 | Furthermore, antisense treatment and pharmacological studies indicated that the novel isoform PKCdelta and PKD are both required for PMA- and DAG-induced MARCKS phosphorylation and hyperpermeability in pulmonary microvascular endothelial cells, whereas isoforms alpha, betaI, and epsilon were dispensable with regard to these same phenomena. | Diglycerides | myristoylated alanine rich protein kinase C substrate | Homo sapiens |