Title : Effects of insulin-like growth factor-II on proliferation and differentiation of ovarian granulosa cells.

Pub. Date : 1992

PMID : 1337056






2 Functional Relationships(s)
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1 Treatment with 100 ng/ml IGF-II produced a significant increase in the basal accumulation of cyclic AMP in porcine granulosa cells. Cyclic AMP insulin like growth factor 2 Homo sapiens
2 Our findings suggest that IGF-II may be a general stimulator in the proliferation and differentiation of granulosa cells, and that cyclic AMP may be a second messenger for the effects of IGF-II in ovarian granulosa cells. Cyclic AMP insulin like growth factor 2 Homo sapiens