Pub. Date : 1992 Sep
PMID : 1330154
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Preincubation with the PKC inhibitor Ro-31-8220 abolished both TPA- and vasopressin-stimulated [3H]-PtdBuOH, suggesting that the intermediate activation of protein kinase C is involved in the regulation of PLD by vasopressin. | Ro 31-8220 | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 2 | Pretreatment of the A10 VSMC with Ro-31-8220 (100 microM) also potentiated vasopressin-stimulated Ins(1,4,5)P3 mass formation.Therefore stimulation of PKC may have opposing roles in the regulation of agonist activation of PLC and PLD.7. | Ro 31-8220 | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |