Title : Endothelium-derived relaxing factor inhibits thrombin-induced platelet aggregation by inhibiting platelet phospholipase C.

Pub. Date : 1992 Jan 1

PMID : 1309423






1 Functional Relationships(s)
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1 EC significantly blocked the thrombin stimulated breakdown of phosphatidylinositol-4,5-bisphosphate (PIP2) and the production of phosphatidic acid in [32P]orthophosphate-labeled platelets and of inositol trisphosphate in [3H]myoinositol-labeled platelets. Inositol coagulation factor II, thrombin Homo sapiens