Title : Urinary 6 beta-hydroxycortisol/cortisol ratios measured by high-performance liquid chromatography for use as a biomarker for the human cytochrome P-450 3A4.

Pub. Date : 1992 Nov-Dec

PMID : 1302569






1 Functional Relationships(s)
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1 Cortisol is metabolized to 6 beta-hydroxycortisol by the human cytochrome P-450 3A4, an enzyme implicated in the critical epoxidation reactions of aflatoxin B1 and certain polycyclic aromatic hydrocarbons. Polycyclic Aromatic Hydrocarbons cytochrome P450 family 3 subfamily A member 4 Homo sapiens