Title : Corticotropin-releasing factor mediates the antinociceptive action of nitrous oxide in rats.

Pub. Date : 2003 Sep

PMID : 12960557






2 Functional Relationships(s)
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1 RESULTS: Inhalation of nitrous oxide induced a dose-dependent increase in c-Fos expression in CRF-positive neurons in the paraventricular nucleus of the hypothalamus. Nitrous Oxide Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 Intracerebroventricular administration of CRF antagonist inhibited nitrous oxide-induced c-Fos expression in the locus ceruleus and the antinociceptive effect of nitrous oxide. Nitrous Oxide Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus