Pub. Date : 2003 Sep 1
PMID : 12948857
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Decreased Erk activity in the presence of heparin preceded, and may account for, decreased MKP-1. | Heparin | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | However, because MKP-1 is known to cause an increase in activity of kinases upstream of Erk, that may signal through additional pathways, the decrease in MKP-1 activity may paradoxically enhance heparin"s antiproliferative effects. | Heparin | mitogen-activated protein kinase 1 | Homo sapiens |