Title : ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer.

Pub. Date : 2003 Sep 1

PMID : 12947056






1 Functional Relationships(s)
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1 K-ras codon 13 mutations (all with G-A nucleotide transitions resulting in Gly>Asp substitution) and single activating mutations in any of the ras genes were also independent predictors of poor survival in differentiated thyroid carcinomas (P =.027 and P =.007, respectively). Glycine KRAS proto-oncogene, GTPase Homo sapiens