Pub. Date : 2003 Jul
PMID : 12930673
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Sodium fluoride could stimulate the proliferation of osteoblast in rats with chronic fluorosis and induce expression of both c-fos and c-jun in all envelops of the spine bone, as compared with its control group. | Sodium Fluoride | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 2 | Value of optical absorption in mRNA expression of c-fos and c-jun was 139.63 and 126.37, respectively, in rats with NaF plus high-calcium, significantly lower than that in control group with high-calcium only (107.74 and 117.48, respectively) (P < 0.001). | Sodium Fluoride | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 3 | Western blotting showed that level of protein expression of c-fos and c-jun in periosteal osteoblasts was significantly higher in all rat groups with NaF than that in all control groups, with values of optical absorption of 123.32, 116.60, 115.97 and 108.30, respectively. | Sodium Fluoride | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 4 | mRNA expression of c-fos and c-jun in osteoblast-like cells treated with NaF for 12 h increased obviously, and remained at high level 48 h after exposure, with values of optical absorption of 114.80, 161.14, 118.20, and 150.41, respectively, as compared with that in control group (P < 0.001 and P < 0.05). | Sodium Fluoride | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |