Title : Role of the IGF-II receptor in mediating acute, non-genomic effects of retinoids and IGF-II on keratinocyte cell death.

Pub. Date : 2003 Aug

PMID : 12930299






2 Functional Relationships(s)
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1 Interestingly, insulin-like growth factor-II (IGF-II, 50 ng/ml) was able to significantly (67.3%; P < 0.05) reduce RA effects, whereas IGF-I (50 ng/ml) and insulin (75 ng/ml) were without effect. Tretinoin insulin like growth factor 2 Homo sapiens
2 The inhibition of RA action by IGF-II was independent of its ability to signal through the IGF-I receptor or to interact with IGFBPs. Tretinoin insulin like growth factor 2 Homo sapiens