Title : SR141716A-sensitive enhancement of ET-1 hypotensive effect by chronic NOS inhibition.

Pub. Date : 2003 Oct

PMID : 12913062






1 Functional Relationships(s)
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1 The enhanced ET-1 hypotensive effect in L-NAME-treated rats was abolished by the ETB receptor antagonist BQ-788 but was unaltered by the cyclooxygenase inhibitor diclofenac, the cytochrome P450 inhibitor fluconazole, or the potassium channel blockers apamin, glibenclamide, tetraethylammonium, and 4-aminopyridine. Tetraethylammonium endothelin 1 Rattus norvegicus