Title : The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide.

Pub. Date : 2003 Aug 1

PMID : 12907245






1 Functional Relationships(s)
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1 Vinblastine, doxorubicin, or etoposide (VP-16) induced apoptotic cell death in KB-3 carcinoma cells, with similar kinetic profiles of PARP cleavage, caspase 3 activation, and mitochondrial cytochrome c release. Etoposide poly(ADP-ribose) polymerase 1 Homo sapiens