Title : Long-term pharmacokinetic study of the novel combination of tacrolimus and sirolimus in de novo renal allograft recipients.

Pub. Date : 2003 Aug

PMID : 12883227






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1 Dose reductions of tacrolimus in both study groups were reflected by concordant decreasing pharmacokinetic exposure parameters, which illustrates the common clinical practice of reducing the dose of calcineurin inhibitor as time elapses after transplantation. Tacrolimus calcineurin binding protein 1 Homo sapiens