Title : Comparison of the closed conformation of the beta 1,4-galactosyltransferase-1 (beta 4Gal-T1) in the presence and absence of alpha-lactalbumin (LA).

Pub. Date : 2003 Aug

PMID : 12854954






2 Functional Relationships(s)
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1 The closed conformation induced by the sugar acceptors or the less preferred donor substrates has been observed only when complexed with LA. Sugars lactalbumin alpha Homo sapiens
2 We have also further refined the structures of beta 4Gal-T1.LA complexes containing the sugar acceptor and the less preferred sugar nucleotide donor substrates and compared the conformational changes in the enzyme induced by substrates with and without LA. Sugars lactalbumin alpha Homo sapiens