Title : Tomato and soy polyphenols reduce insulin-like growth factor-I-stimulated rat prostate cancer cell proliferation and apoptotic resistance in vitro via inhibition of intracellular signaling pathways involving tyrosine kinase.

Pub. Date : 2003 Jul

PMID : 12840208






1 Functional Relationships(s)
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1 Several polyphenols suppressed phosphorylation of AKT and ERK1/2, and more potently inhibited IRS-1 tyrosyl phosphorylation after IGF-I exposure. Polyphenols AKT serine/threonine kinase 1 Rattus norvegicus