Pub. Date : 2003 Oct 15
PMID : 12829604
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Through the use of mutant Chinese hamster ovary (CHO) cell lines defective in glycosaminoglycans (GAGs) biosynthesis as well as the enzymatic removal of specific cell surface GAGs, the molecular identity of the EMR2 ligand was identified as chondroitin sulfate (CS). | Chondroitin Sulfates | adhesion G protein-coupled receptor E2 | Homo sapiens |
| 2 | Through the use of mutant Chinese hamster ovary (CHO) cell lines defective in glycosaminoglycans (GAGs) biosynthesis as well as the enzymatic removal of specific cell surface GAGs, the molecular identity of the EMR2 ligand was identified as chondroitin sulfate (CS). | Chondroitin Sulfates | adhesion G protein-coupled receptor E2 | Homo sapiens |
| 3 | Thus, exogenous CS GAGs blocked the EMR2-ligand interaction in a dose-dependent manner. | Chondroitin Sulfates | adhesion G protein-coupled receptor E2 | Homo sapiens |
| 4 | EMR2-CS interaction is Ca2+- and sulphation-dependent and results in cell attachment. | Chondroitin Sulfates | adhesion G protein-coupled receptor E2 | Homo sapiens |