CPRiL

ADGRE2

adhesion G protein-coupled receptor E2

This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

• adhesion G protein-coupled receptor E2
• CD97 antigen
• EGF-like module-containing mucin-like hormone receptor-like 2
Leukocyte antigen CD97
egf-like module containing, mucin-like, hormone receptor-like 2
CD312
CD97
EMR2
VBU