Title : Induction of thymidine phosphorylase expression by Taxol does not enhance Furtulon sensitivity in a cisplatin-resistant human ovarian carcinoma cell line.

Pub. Date : 2003 Mar-Apr

PMID : 12820419






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 This product can form 5-fluoro-2"-deoxyuridine 5"-monophosphate (FdUMP) through the action of thymidine kinase, and FdUMP in turn can inhibit thymidylate synthase (TS), leading to reduced thymidylate formation and subsequent inhibition of DNA synthesis. Fluorodeoxyuridylate thymidylate synthetase Homo sapiens
2 This product can form 5-fluoro-2"-deoxyuridine 5"-monophosphate (FdUMP) through the action of thymidine kinase, and FdUMP in turn can inhibit thymidylate synthase (TS), leading to reduced thymidylate formation and subsequent inhibition of DNA synthesis. Fluorodeoxyuridylate thymidylate synthetase Homo sapiens