Title : Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function.

Pub. Date : 2003 Aug 29

PMID : 12815057






1 Functional Relationships(s)
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1 Furthermore, individually mutating hSpry2 residues 52-59 to alanine indicated a tight correlation between their affinity for c-Cbl binding and their inhibition of ERK2 activity in the FGFR pathway. Alanine Cbl proto-oncogene Homo sapiens