Title : Angiotensin II activates extracellular signal regulated kinases via protein kinase C and epidermal growth factor receptor in breast cancer cells.

Pub. Date : 2003 Aug

PMID : 12811831






1 Functional Relationships(s)
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1 The Ang II-induced proliferation of breast cancer cells was reduced by (a) Go6976, an inhibitor of conventional PKC-alpha and -beta1, (b) AG1478, an inhibitor of the tyrosine kinase of the EGF receptor (EGFR), and (c) downregulation of 1,2-diacylglycerol-sensitive PKCs achieved by phorbol 12-myristate 13-acetate (PMA). Tyrosine angiotensinogen Homo sapiens