Title : Activation of PPARalpha and PPARgamma by environmental phthalate monoesters.

Pub. Date : 2003 Aug

PMID : 12805656






2 Functional Relationships(s)
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1 Activation of PPARalpha and PPARgamma by environmental phthalate monoesters. phthalic acid peroxisome proliferator activated receptor alpha Homo sapiens
2 Human exposure to other phthalate monoesters, including metabolites of di-n-butyl phthalate and butyl benzyl phthalate, is substantially higher than that of MEHP, prompting this investigation of their potential for PPAR activation, assayed in COS cells and in PPAR-responsive liver (PPARalpha) and adipocyte (PPARgamma) cell lines. phthalic acid peroxisome proliferator activated receptor alpha Homo sapiens